Improving attention function in children with ADHD

The Treatment

EndeavorRx is an ADHD treatment for kids aged 8-17. It’s delivered through an immersive video game experience on mobile devices.

Created by world-class neuroscientists and award-winning game designers, it targets areas of the brain that play a key role in attention function.

As an FDA-authorized medical device, EndeavorRx must be prescribed by a healthcare professional. It should be considered for use as part of a therapeutic program.

How EndeavorRx works

EndeavorRx uses sensory stimuli and motor challenges to target areas of the brain that play a key role in attention function.

Kids are challenged to multitask and ignore distractions by navigating courses, collecting targets, and avoiding obstacles.

An algorithm measures performance and customizes each patient’s treatment in real time.

EndeavorRx is typically played for 25 minutes, 5 days a week, for at least 4 consecutive weeks, or as prescribed.

Parents can follow their child’s treatment with the EndeavorRx Insight® app to track daily efforts and level completion.

What’s it like to play?

EndeavorRx challenges players to chase mystic creatures, race through different worlds, and use boosts to problem‑solve while building their very own universe.

Discover The Treatment



It’s supposed
to be difficult!

The game is meant to be challenging, so make sure to encourage your child while they play.

Want your child to try EndeavorRx?

Try our free demo


© Copyright 2022 Akili Interactive


Indications, Safety and Cautions

EndeavorRx is a digital therapeutic indicated to improve attention function as measured by computer-based testing in children ages 8-17 years old with primarily inattentive or combined-type ADHD, who have a demonstrated attention issue. Patients who engage with EndeavorRx demonstrate improvements in a digitally assessed measure, Test of Variables of Attention (TOVA®), of sustained and selective attention and may not display benefits in typical behavioral symptoms, such as hyperactivity. EndeavorRx should be considered for use as part of a therapeutic program that may include clinician-directed therapy, medication, and/or educational programs, which further address symptoms of the disorder.

No serious adverse events were reported. Of 342 participants who received AKL-T01 in the two clinical trials supporting EndeavorRx authorization for age ranges 8-17, 17 participants (4.97%) experienced treatment-related adverse events (TE-ADE) (possible, probable, likely). TE-ADEs reported at greater than 1% across the studies include: frustration tolerance decreased (2.34%) and headache (1.17%). Other adverse events occurred less than 1% and included dizziness, emotional disorder, nausea, and aggression. All adverse events were transient and no events led to device discontinuation. Across other studies in children and adolescents with ADHD, rates of adverse events were similarly low (<10%) and no Serious Adverse Events have been reported. All reported adverse events across all clinical trials resolved at the end of treatment. Users should consider the totality of evidence presented along with their health care provider when considering incorporating AKL-T01 into their treatment plan.

Rx only: Federal law restricts this device to sale by or on the order of a licensed health care provider. EndeavorRx should only be used by the patient for whom the prescription was written. For medical questions, please contact your child’s healthcare provider. If you are experiencing a medical emergency, please dial 911. EndeavorRx is not intended to be used as a stand-alone therapeutic and is not a substitution for your child’s medication.

If your child experiences frustration, emotional reaction, dizziness, nausea, headache, eye-strain, or joint pain while playing EndeavorRx pause the treatment. If the problem persists contact your child’s healthcare provider. If your child experiences a seizure stop the treatment and contact your child’s healthcare provider.

EndeavorRx may not be appropriate for patients with photo-sensitive epilepsy, color blindness, or physical limitations that restrict use of a mobile device; parents should consult with their child’s healthcare provider.

Please follow all of your mobile device manufacturer’s instructions for the safe operation of your mobile device. For example, this may include appropriate volume settings, proper battery charging, not operating the device if damaged, and proper device disposal. Contact your mobile device manufacturer for any questions or concerns that pertain to your device.